Hematopoietic cell transplantation for asymptomatic X-linked lymphoproliferative syndrome type 1
نویسندگان
چکیده
منابع مشابه
Hematopoietic Stem Cell Transplantation for Thalassemia
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متن کاملDeficient natural killer cell activity in x-linked lymphoproliferative syndrome.
The activity of natural killer cells was found to be deficient in 10 of 12 males with X-linked lymphoproliferative syndrome, a life-threatening proliferation of lymphocytes after infection by Epstein-Barr virus. The activity levels of natural killer cells from affected males were increased after treatment with interferon in vitro, but normal levels of killing were not obtained. Deficient activi...
متن کاملX-Linked Lymphoproliferative Disease
2B4 is a surface molecule involved in activation of the natural killer (NK) cell-mediated cytotoxicity. It binds a protein termed Src homology 2 domain-containing protein (SH2D1A) or signaling lymphocyte activation molecule (SLAM)-associated protein (SAP), which in turn has been proposed to function as a regulator of the 2B4-associated signal transduction pathway. In this study, we analyzed pat...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2018
ISSN: 1710-1492
DOI: 10.1186/s13223-018-0306-1